1909 - A Modern Dr. Jekyll

 Among the first of film parodies and comedic retellings of Strange Case of Dr. Jekyll and Mr. Hyde is Kenyon's 1909 A Modern Dr. Jekyll. Similar to many films of the day, the film today is lost media. However, while unwatchable today, the film is cited as both the first comedic adaptation as well as the first including a male-to-female transformation, a trope which would continue in popularity to the present day. Instead of only having a transformation to Edward Hyde, Dr. Henry Jekyll undergoes transformations into multiple personas whilst evading law enforcement in this film. While the actor for Dr. Jekyll and Mr. Hyde isn't confirmed, it is considered most likely that he was 34-year old Henry Arthur Barrows. The identity of director Kenyon, however, remains anonymous.